Drosophila fly article dating before 1950
This gene gets its name due to the segmented expression pattern which is thought to resemble a tarpaulin covering an 18-wheeler truck.
This gene encodes a transcription factor which is involved in the formation of heart and dorsal vascular musculature.
The team of scientists studied the function of a special developmental gene of the Hox gene family.
melanogaster continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution.
Boss gene encodes a cell-surface receptor tyrosine kinase and this gene helps in photoreceptor cell (R-cell) development in the Drosophila compound eye.
But despite several attempts, the identity of this of this male killer has remained a mystery.
Now, Professor Bruno Lemaitre and Dr Toshiyuki Harumoto at EPFL have identified the elusive male-killing bacterial factor, solving the mystery. The gene for Spaid is known to encode a protein that has particular structural characteristics needed for its localization and activity inside the bacterium (ankyrin repeats and de-ubiquitinase domains).
"To our knowledge, Spaid is the first bacterial effector protein identified to date that affects host cellular machinery in a sex-specific manner," says Harumoto.
"And it is also, to our knowledge again, the first paper to identify an insect endosymbiont factor causing male killing.